Anti-Recombinant-WARS1 antibody [RM1S33] (STJA0024215)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Tryptophan--Trna Ligase-Cytoplasmic for use in FC, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1S33 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | FCM: 1:20-1:100 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | WARS1 |
| Gene ID | 7453 |
| Uniprot ID | SYWC_HUMAN |
Additional Info
| Function | Catalyzes the attachment of tryptophan to tRNA(Trp) in a two-step reaction: tryptophan is first activated by ATP to form Trp-AMP and then transferred to the acceptor end of the tRNA(Trp). Isoform 1: Has no angiostatic activity. T2-TrpRS: Possesses an angiostatic activity but has no aminoacylation activity. Inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression. Isoform 2: Has an angiostatic activity. |
| Protein Name | Tryptophan--Trna Ligase - CytoplasmicInterferon-Induced Protein 53Ifp53Tryptophanyl-Trna SynthetaseTrprsHwrs Cleaved Into - T1-Trprs - T2-Trprs |
| Database Links | Reactome: R-HSA-379716 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Tryptophan--Trna Ligase - Cytoplasmic antibodyAnti-Interferon-Induced Protein 53 antibodyAnti-Ifp53 antibodyAnti-Tryptophanyl-Trna Synthetase antibodyAnti-Trprs antibodyAnti-Hwrs Cleaved Into - T1-Trprs - T2-Trprs antibodyAnti-WARS1 antibodyAnti-IFI53 antibodyAnti-WARS antibodyAnti-WRS antibody |
Information sourced from Uniprot.org