Anti-Recombinant-VGAT antibody (N-Term) [L118/80] (STJA0040499)
SPECIFICATIONS
ClonalityMonoclonal
HostChicken
ConjugationUnconjugated
IsotypeIgY
ImmunogenFusion protein amino acids 1-133 (cytoplasmic N-terminus) of mouse VGAT (accession number O35633) produced recombinantly in E. Coli
General Information
| Short Description | Chicken monoclonal anti-Recombinant-VGAT (N-Term) for use in WB, IHC, ICC and ELISA in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/ICC/ELISA |
| Host | Chicken |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | L118/80 |
| Isotype | IgY |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by affinity chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:100ICC 1:100 |
| Formulation | PBS |
| Storage Instruction | Aliquot and store at ≤-20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap. |
Target Information
| Gene Symbol | Slc32a1 |
| Gene ID | 22348 |
| Uniprot ID | VIAAT_MOUSE |
| Immunogen | Fusion protein amino acids 1-133 (cytoplasmic N-terminus) of mouse VGAT (accession number O35633) produced recombinantly in E. Coli |
| Immunogen Region | N-Term |
| Immunogen Sequence | Mouse |
| Specificity | No cross-reactivity reported |
Additional Info
| Function | Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake. |
| Protein Name | Vesicular Inhibitory Amino Acid TransporterSolute Carrier Family 32 Member 1Vesicular Gaba And Glycine TransporterVesicular Gaba TransporterMvgatMviaat |
| Database Links | Reactome: R-MMU-425393Reactome: -MMU-888590 |
| Cellular Localisation | Cytoplasmic Vesicle MembraneMulti-Pass Membrane ProteinPresynapsePresents In Glycine-Gaba- Or Gaba- And Glycine-Containing Boutons |
| Alternative Antibody Names | Anti-Vesicular Inhibitory Amino Acid Transporter antibodyAnti-Solute Carrier Family 32 Member 1 antibodyAnti-Vesicular Gaba And Glycine Transporter antibodyAnti-Vesicular Gaba Transporter antibodyAnti-Mvgat antibodyAnti-Mviaat antibodyAnti-Slc32a1 antibodyAnti-Vgat antibodyAnti-Viaat antibody |
Information sourced from Uniprot.org