Anti-Recombinant-VAV2 antibody [RM1Y65] (STJA0024841)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Guanine Nucleotide Exchange Factor Vav2 for use in IF, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1Y65 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | VAV2 |
| Gene ID | 7410 |
| Uniprot ID | VAV2_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated on tyrosine residues in response to FGR activation. |
| Function | Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. |
| Protein Name | Guanine Nucleotide Exchange Factor Vav2Vav-2 |
| Database Links | Reactome: R-HSA-114604Reactome: R-HSA-193648Reactome: R-HSA-2029482Reactome: R-HSA-2424491Reactome: R-HSA-2871796Reactome: R-HSA-2871809Reactome: R-HSA-3928665Reactome: R-HSA-416482Reactome: R-HSA-4420097Reactome: R-HSA-445144Reactome: R-HSA-5218920Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013408Reactome: R-HSA-9013423Reactome: R-HSA-9664422Reactome: R-HSA-9748787 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Guanine Nucleotide Exchange Factor Vav2 antibodyAnti-Vav-2 antibodyAnti-VAV2 antibody |
Information sourced from Uniprot.org