Anti-Recombinant-Vav1/2/3 antibody [RM1P80] (STJA0023965)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJA0023965
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General Information

Short DescriptionRabbit monoclonal anti-Recombinant-Proto-Oncogene Vav for use in FC, IF, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsFC/IF/IP/WB
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDRM1P80
IsotypeIgG
ConjugationUnconjugated
PurificationProtein A/G purified from cell culture supernatant
Dilution RangeFCM: 1:20-1:100
Formulation0.01M PBS
Storage InstructionSuitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.

Target Information

Gene SymbolVAV1
Gene ID7409
Uniprot IDVAV_HUMAN

Additional Info

Post Translational Modifications Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS). Phosphorylated by FYN.
Function Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Protein Name Proto-Oncogene Vav
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-1257604
Reactome: R-HSA-1433557
Reactome: R-HSA-193648
Reactome: R-HSA-2029482
Reactome: R-HSA-2219530
Reactome: R-HSA-2871796
Reactome: R-HSA-2871809
Reactome: R-HSA-389359
Reactome: R-HSA-416482
Reactome: R-HSA-4420097
Reactome: R-HSA-512988
Reactome: R-HSA-5218920
Reactome: R-HSA-6811558
Reactome: R-HSA-8980692
Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013408
Reactome: R-HSA-9027284
Reactome: R-HSA-912631
Reactome: R-HSA-9664422
Reactome: R-HSA-9679191
Reactome: R-HSA-9748787
Reactome: R-HSA-983695
Cellular Localisation
Alternative Antibody Names Anti-Proto-Oncogene Vav antibody
Anti-VAV1 antibody
Anti-VAV antibody

Information sourced from Uniprot.org

Citations

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