Anti-Recombinant-TRPC1/TRP-1 antibody [RM1X22] (STJA0024699)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Short Transient Receptor Potential Channel 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1X22 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | TRPC1 |
| Gene ID | 7220 |
| Uniprot ID | TRPC1_HUMAN |
Additional Info
| Post Translational Modifications | Activation of PRKCA induces phosphorylation of TRPC1 and subsequent Ca2+ entry into cells. |
| Function | Forms a receptor-activated non-selective calcium permeant cation channel. Forms a heteromeric ion channel with TRPC4 or TRPC5 that has reduced calcium permeability compared to the homomeric TRPC4 or TRPC5 channel. Also permeable to monovalent ions including sodium, lithium and cesium ions. Isoform Short: Forms a receptor-activated non-selective calcium permeant cation channel. Also activated by intracellular calcium store depletion. |
| Protein Name | Short Transient Receptor Potential Channel 1Trpc1Transient Receptor Protein 1Trp-1 |
| Database Links | Reactome: R-HSA-3295583Reactome: R-HSA-418890Reactome: R-HSA-5578775Reactome: R-HSA-983695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Short Transient Receptor Potential Channel 1 antibodyAnti-Trpc1 antibodyAnti-Transient Receptor Protein 1 antibodyAnti-Trp-1 antibodyAnti-TRPC1 antibodyAnti-TRP1 antibody |
Information sourced from Uniprot.org