Anti-Recombinant-TPP1 antibody [RM1D28] (STJA0022923)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Tripeptidyl-Peptidase 1 for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1D28 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:50-1:100 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | TPP1 |
| Gene ID | 1200 |
| Uniprot ID | TPP1_HUMAN |
Additional Info
| Post Translational Modifications | Activated by autocatalytic proteolytical processing upon acidification. N-glycosylation is required for processing and activity. |
| Function | Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus. |
| Protein Name | Tripeptidyl-Peptidase 1Tpp-1Cell Growth-Inhibiting Gene 1 ProteinLysosomal Pepstatin-Insensitive ProteaseLpicTripeptidyl AminopeptidaseTripeptidyl-Peptidase ITpp-I |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | LysosomeMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Tripeptidyl-Peptidase 1 antibodyAnti-Tpp-1 antibodyAnti-Cell Growth-Inhibiting Gene 1 Protein antibodyAnti-Lysosomal Pepstatin-Insensitive Protease antibodyAnti-Lpic antibodyAnti-Tripeptidyl Aminopeptidase antibodyAnti-Tripeptidyl-Peptidase I antibodyAnti-Tpp-I antibodyAnti-TPP1 antibodyAnti-CLN2 antibodyAnti-GIG1 antibodyAnti-UNQ267 antibodyAnti-PRO304 antibody |
Information sourced from Uniprot.org