| Post Translational Modifications | Activated by autocatalytic proteolytical processing upon acidification. N-glycosylation is required for processing and activity. |
| Function | Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus. |
| Protein Name | Tripeptidyl-Peptidase 1Tpp-1Cell Growth-Inhibiting Gene 1 ProteinLysosomal Pepstatin-Insensitive ProteaseLpicTripeptidyl AminopeptidaseTripeptidyl-Peptidase ITpp-I |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | LysosomeMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Tripeptidyl-Peptidase 1 antibodyAnti-Tpp-1 antibodyAnti-Cell Growth-Inhibiting Gene 1 Protein antibodyAnti-Lysosomal Pepstatin-Insensitive Protease antibodyAnti-Lpic antibodyAnti-Tripeptidyl Aminopeptidase antibodyAnti-Tripeptidyl-Peptidase I antibodyAnti-Tpp-I antibodyAnti-TPP1 antibodyAnti-CLN2 antibodyAnti-GIG1 antibodyAnti-UNQ267 antibodyAnti-PRO304 antibody |
Information sourced from Uniprot.org
