Anti-CLN2/TPP1 antibody (Internal) (STJ72001)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CLN2/TPP1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Dog/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 65kDa band observed in Human Placenta lysates (calculated MW of 61.2kDa according to NP_000382.3). Recommended concentration: 0.3-1µg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | TPP1 |
| Gene ID | 1200 |
| Uniprot ID | TPP1_HUMAN |
| Accession Number | NP_000382.3 |
| Immunogen Region | Internal |
| Immunogen Sequence | TPSVIRKRYNLTSQD |
Additional Info
| Post Translational Modifications | Activated by autocatalytic proteolytical processing upon acidification. N-glycosylation is required for processing and activity. |
| Function | Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus. |
| Protein Name | Tripeptidyl-Peptidase 1Tpp-1Cell Growth-Inhibiting Gene 1 ProteinLysosomal Pepstatin-Insensitive ProteaseLpicTripeptidyl AminopeptidaseTripeptidyl-Peptidase ITpp-I |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | LysosomeMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Tripeptidyl-Peptidase 1 antibodyAnti-Tpp-1 antibodyAnti-Cell Growth-Inhibiting Gene 1 Protein antibodyAnti-Lysosomal Pepstatin-Insensitive Protease antibodyAnti-Lpic antibodyAnti-Tripeptidyl Aminopeptidase antibodyAnti-Tripeptidyl-Peptidase I antibodyAnti-Tpp-I antibodyAnti-TPP1 antibodyAnti-CLN2 antibodyAnti-GIG1 antibodyAnti-UNQ267 antibodyAnti-PRO304 antibody |
Information sourced from Uniprot.org