Anti-Recombinant-TNFAIP8 antibody [RM1G45] (STJA0023237)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Tumor Necrosis Factor Alpha-Induced Protein 8 for use in IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1G45 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IP: 1:20 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | TNFAIP8 |
| Gene ID | 25816 |
| Uniprot ID | TFIP8_HUMAN |
Additional Info
| Function | Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. |
| Protein Name | Tumor Necrosis Factor Alpha-Induced Protein 8Tnf Alpha-Induced Protein 8Head And Neck Tumor And Metastasis-Related ProteinMdc-3.13Nf-Kappa-B-Inducible Ded-Containing ProteinNdedScc-S2Tnf-Induced Protein Gg2-1 |
| Database Links | Reactome: R-HSA-1483255 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Alpha-Induced Protein 8 antibodyAnti-Tnf Alpha-Induced Protein 8 antibodyAnti-Head And Neck Tumor And Metastasis-Related Protein antibodyAnti-Mdc-3.13 antibodyAnti-Nf-Kappa-B-Inducible Ded-Containing Protein antibodyAnti-Nded antibodyAnti-Scc-S2 antibodyAnti-Tnf-Induced Protein Gg2-1 antibodyAnti-TNFAIP8 antibody |
Information sourced from Uniprot.org