Anti-Recombinant-TFAP2A antibody [RM1K36] (STJA0023525)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Transcription Factor Ap-2-Alpha for use in IP and WB in Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IP/WB |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1K36 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IP: 1:20 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | TFAP2A |
| Gene ID | 7020 |
| Uniprot ID | AP2A_HUMAN |
Additional Info
| Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. |
| Protein Name | Transcription Factor Ap-2-AlphaAp2-AlphaAp-2 Transcription FactorActivating Enhancer-Binding Protein 2-AlphaActivator Protein 2Ap-2 |
| Database Links | Reactome: R-HSA-3232118 P05549-1Reactome: R-HSA-8864260Reactome: R-HSA-8866904Reactome: R-HSA-8866906Reactome: R-HSA-8866907Reactome: R-HSA-8866910Reactome: R-HSA-8866911Reactome: R-HSA-8869496Reactome: R-HSA-9824585Reactome: R-HSA-9834899 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Ap-2-Alpha antibodyAnti-Ap2-Alpha antibodyAnti-Ap-2 Transcription Factor antibodyAnti-Activating Enhancer-Binding Protein 2-Alpha antibodyAnti-Activator Protein 2 antibodyAnti-Ap-2 antibodyAnti-TFAP2A antibodyAnti-AP2TF antibodyAnti-TFAP2 antibody |
Information sourced from Uniprot.org