Anti-Recombinant-SULT1E1 antibody [SAA0758] (STJA0019602)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Recombinant-Sulfotransferase 1e1 antibody for use in ELISA and WB in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0758 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | SULT1E1 |
| Gene ID | 6783 |
| Uniprot ID | ST1E1_HUMAN |
Additional Info
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. Is a key enzyme in estrogen homeostasis, the sulfation of estrogens leads to their inactivation. Also sulfates dehydroepiandrosterone (DHEA), pregnenolone, (24S)-hydroxycholesterol and xenobiotic compounds like ethinylestradiol, equalenin, diethyl stilbesterol and 1-naphthol at significantly lower efficiency. Does not sulfonate cortisol, testosterone and dopamine. May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system. |
| Protein Name | Sulfotransferase 1e1St1e1Est-1Estrogen SulfotransferaseSulfotransferase - Estrogen-Preferring |
| Database Links | Reactome: R-HSA-156584Reactome: R-HSA-9753281 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Sulfotransferase 1e1 antibodyAnti-St1e1 antibodyAnti-Est-1 antibodyAnti-Estrogen Sulfotransferase antibodyAnti-Sulfotransferase - Estrogen-Preferring antibodyAnti-SULT1E1 antibodyAnti-STE antibody |
Information sourced from Uniprot.org