Anti-Recombinant-STX4 antibody [RM2D41] (STJA0025312)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Syntaxin-4 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2D41 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | STX4 |
| Gene ID | 6810 |
| Uniprot ID | STX4_HUMAN |
Additional Info
| Function | Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. In neurons, recruited at neurite tips to membrane domains rich in the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC) which promotes neurite tip surface expression of the dopamine transporter SLC6A3/DAT by facilitating fusion of SLC6A3-containing transport vesicles with the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes and in docking of synaptic vesicles at presynaptic active zones. Required for normal hearing. |
| Protein Name | Syntaxin-4Renal Carcinoma Antigen Ny-Ren-31 |
| Database Links | Reactome: R-HSA-114516Reactome: R-HSA-1236974Reactome: R-HSA-1445148Reactome: R-HSA-199992Reactome: R-HSA-449836 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iv Membrane ProteinCell ProjectionNeuron ProjectionStereociliumLocalizes To Neurite Tips In Neuronal Cells |
| Alternative Antibody Names | Anti-Syntaxin-4 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-31 antibodyAnti-STX4 antibodyAnti-STX4A antibody |
Information sourced from Uniprot.org