Anti-Recombinant-STMN1 antibody [RM1B95] (STJA0026865)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Stathmin for use in FC, IF, IHC, IP and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1B95 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | STMN1 |
| Gene ID | 3925 |
| Uniprot ID | STMN1_HUMAN |
Additional Info
| Post Translational Modifications | Many different phosphorylated forms are observed depending on specific combinations among the sites which can be phosphorylated. MAPK is responsible for the phosphorylation of stathmin in response to NGF. Phosphorylation at Ser-16 seems to be required for neuron polarization. Phosphorylation at Ser-63 reduces tubulin binding 10-fold and suppresses the MT polymerization inhibition activity. |
| Function | Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear. |
| Protein Name | StathminLeukemia-Associated Phosphoprotein P18MetablastinOncoprotein 18Op18Phosphoprotein P19Pp19ProsolinProtein Pr22Pp17 |
| Database Links | Reactome: R-HSA-1251985 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Stathmin antibodyAnti-Leukemia-Associated Phosphoprotein P18 antibodyAnti-Metablastin antibodyAnti-Oncoprotein 18 antibodyAnti-Op18 antibodyAnti-Phosphoprotein P19 antibodyAnti-Pp19 antibodyAnti-Prosolin antibodyAnti-Protein Pr22 antibodyAnti-Pp17 antibodyAnti-STMN1 antibodyAnti-C1orf215 antibodyAnti-LAP18 antibodyAnti-OP18 antibody |
Information sourced from Uniprot.org