| Host: | Rabbit |
| Applications: | IF/IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Recombinant-Serine/Threonine-Protein Kinase 33 for use in IF, IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | RM2Q42 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | STK33 |
| Gene ID: | 65975 |
| Uniprot ID: | STK33_HUMAN |
| Post Translational Modifications | Autophosphorylated. |
| Function | Serine/threonine protein kinase required for spermatid differentiation and male fertility. Promotes sperm flagella assembly during spermatogenesis by mediating phosphorylation of fibrous sheath proteins AKAP3 and AKAP4. Also phosphorylates vimentin/VIM, thereby regulating the dynamic behavior of the intermediate filament cytoskeleton. |
| Protein Name | Serine/Threonine-Protein Kinase 33 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonPerinuclear RegionColocalizes With The Caudal End Of The ManchetteA Transient Structure That Guides Tail Elongation In Elongating Spermatids |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase 33 antibodyAnti-STK33 antibody |
Information sourced from Uniprot.org
