Anti-Recombinant-SRSF6 antibody [RM2E10] (STJA0025380)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Serine/Arginine-Rich Splicing Factor 6 for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2E10 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:100-1:200, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | SRSF6 |
| Gene ID | 6431 |
| Uniprot ID | SRSF6_HUMAN |
Additional Info
| Function | Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing. |
| Protein Name | Serine/Arginine-Rich Splicing Factor 6Pre-Mrna-Splicing Factor Srp55Splicing Factor - Arginine/Serine-Rich 6 |
| Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72163Reactome: R-HSA-72165Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856 |
| Cellular Localisation | NucleusNucleus Speckle |
| Alternative Antibody Names | Anti-Serine/Arginine-Rich Splicing Factor 6 antibodyAnti-Pre-Mrna-Splicing Factor Srp55 antibodyAnti-Splicing Factor - Arginine/Serine-Rich 6 antibodyAnti-SRSF6 antibodyAnti-SFRS6 antibodyAnti-SRP55 antibody |
Information sourced from Uniprot.org