Anti-Recombinant-SOS1 antibody [RM2D15] (STJA0025286)

Name: Anti-Recombinant-SOS1 antibody [RM2D15] (STJA0025286)
SKU: STJA0025286
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJA0025286

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General Information

Short Description	Rabbit monoclonal anti-Recombinant-Son Of Sevenless Homolog 1 for use in IF, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	IF/IHC/WB
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Clonality	Monoclonal
Clone ID	RM2D15
Isotype	IgG
Conjugation	Unconjugated
Purification	Protein A/G purified from cell culture supernatant
Dilution Range	IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000
Formulation	0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide
Storage Instruction	Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.

Target Information

Gene Symbol	SOS1
Gene ID	6654
Uniprot ID	SOS1_HUMAN

Additional Info

Post Translational Modifications	Phosphorylation at Ser-1134 and Ser-1161 by RPS6KA3 create YWHAB and YWHAE binding sites and which contribute to the negative regulation of EGF-induced MAPK1/3 phosphorylation.
Function	Promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3/ERK1 in response to EGF. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity.
Protein Name	Son Of Sevenless Homolog 1 Sos-1
Database Links	Reactome: R-HSA-112412 Reactome: R-HSA-1236382 Reactome: R-HSA-1250196 Reactome: R-HSA-1250347 Reactome: R-HSA-1433557 Reactome: R-HSA-1433559 Reactome: R-HSA-167044 Reactome: R-HSA-179812 Reactome: R-HSA-180336 Reactome: R-HSA-186763 Reactome: R-HSA-193648 Reactome: R-HSA-1963640 Reactome: R-HSA-210993 Reactome: R-HSA-2179392 Reactome: R-HSA-2424491 Reactome: R-HSA-2428933 Reactome: R-HSA-2730905 Reactome: R-HSA-2871796 Reactome: R-HSA-2871809 Reactome: R-HSA-354194 Reactome: R-HSA-375165 Reactome: R-HSA-416482 Reactome: R-HSA-428540 Reactome: R-HSA-5637810 Reactome: R-HSA-5654688 Reactome: R-HSA-5654693 Reactome: R-HSA-5654699 Reactome: R-HSA-5654700 Reactome: R-HSA-5654704 Reactome: R-HSA-5654706 Reactome: R-HSA-5654712 Reactome: R-HSA-5654719 Reactome: R-HSA-5655253 Reactome: R-HSA-5655291 Reactome: R-HSA-5655302 Reactome: R-HSA-5655332 Reactome: R-HSA-5673001 Reactome: R-HSA-74749 Reactome: R-HSA-74751 Reactome: R-HSA-8851805 Reactome: R-HSA-8853659 Reactome: R-HSA-8983432 Reactome: R-HSA-9013149 Reactome: R-HSA-9026519 Reactome: R-HSA-9027284 Reactome: R-HSA-9028731 Reactome: R-HSA-9034864 Reactome: R-HSA-912526 Reactome: R-HSA-9607240 Reactome: R-HSA-9634285 Reactome: R-HSA-9664565 Reactome: R-HSA-9665348 Reactome: R-HSA-9665686 Reactome: R-HSA-9670439 Reactome: R-HSA-9673767 Reactome: R-HSA-9673770 Reactome: R-HSA-9679191 Reactome: R-HSA-9680350 Reactome: R-HSA-9703465 Reactome: R-HSA-9703648 Reactome: R-HSA-983695 Reactome: R-HSA-9842663
Cellular Localisation
Alternative Antibody Names	Anti-Son Of Sevenless Homolog 1 antibody Anti-Sos-1 antibody Anti-SOS1 antibody

Information sourced from Uniprot.org

Citations

View product citations for antibody STJA0025286 on CiteAb