Anti-Recombinant-SLC1A3 antibody [RM1W35] (STJA0024613)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Excitatory Amino Acid Transporter 1 for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1W35 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:100-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | SLC1A3 |
| Gene ID | 6507 |
| Uniprot ID | EAA1_HUMAN |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. |
| Protein Name | Excitatory Amino Acid Transporter 1Sodium-Dependent Glutamate/Aspartate Transporter 1Glast-1Solute Carrier Family 1 Member 3 |
| Database Links | Reactome: R-HSA-210455Reactome: R-HSA-210500Reactome: R-HSA-425393Reactome: R-HSA-5619062 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Excitatory Amino Acid Transporter 1 antibodyAnti-Sodium-Dependent Glutamate/Aspartate Transporter 1 antibodyAnti-Glast-1 antibodyAnti-Solute Carrier Family 1 Member 3 antibodyAnti-SLC1A3 antibodyAnti-EAAT1 antibodyAnti-GLAST antibodyAnti-GLAST1 antibody |
Information sourced from Uniprot.org