Anti-Recombinant-RNGTT antibody [RM1E93] (STJA0023087)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Mrna-Capping Enzyme for use in IP and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1E93 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IP: 1:20 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | RNGTT |
| Gene ID | 8732 |
| Uniprot ID | MCE1_HUMAN |
Additional Info
| Function | Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate. |
| Protein Name | Mrna-Capping EnzymeHcap1Hce Includes - Mrna 5'-Triphosphate MonophosphataseMrna 5'-Phosphatase - Mrna GuanylyltransferaseGtp--Rna GuanylyltransferaseGtase |
| Database Links | Reactome: R-HSA-167160Reactome: R-HSA-72086Reactome: R-HSA-77075 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Mrna-Capping Enzyme antibodyAnti-Hcap1 antibodyAnti-Hce Includes - Mrna 5'-Triphosphate Monophosphatase antibodyAnti-Mrna 5'-Phosphatase - Mrna Guanylyltransferase antibodyAnti-Gtp--Rna Guanylyltransferase antibodyAnti-Gtase antibodyAnti-RNGTT antibodyAnti-CAP1A antibody |
Information sourced from Uniprot.org