Anti-Recombinant-RIOX2 antibody [RM2M66] (STJA0026129)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Ribosomal Oxygenase 2 for use in IF and WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2M66 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | RIOX2 |
| Gene ID | 84864 |
| Uniprot ID | RIOX2_HUMAN |
Additional Info
| Function | Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
| Protein Name | Ribosomal Oxygenase 260s Ribosomal Protein L27a Histidine HydroxylaseBifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase MinaHistone Lysine Demethylase MinaMyc-Induced Nuclear AntigenMineral Dust-Induced Gene ProteinNucleolar Protein 52Ribosomal Oxygenase MinaRox |
| Database Links | Reactome: R-HSA-3214842Reactome: R-HSA-9629569 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Ribosomal Oxygenase 2 antibodyAnti-60s Ribosomal Protein L27a Histidine Hydroxylase antibodyAnti-Bifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase Mina antibodyAnti-Histone Lysine Demethylase Mina antibodyAnti-Myc-Induced Nuclear Antigen antibodyAnti-Mineral Dust-Induced Gene Protein antibodyAnti-Nucleolar Protein 52 antibodyAnti-Ribosomal Oxygenase Mina antibodyAnti-Rox antibodyAnti-RIOX2 antibodyAnti-MDIG antibodyAnti-MINA antibodyAnti-MINA53 antibodyAnti-NO52 antibody |
Information sourced from Uniprot.org