Anti-Recombinant-RASA1 antibody [RM1RM70] (STJA0024153)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Ras Gtpase-Activating Protein 1 for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1RM70 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:50-1:100 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | RASA1 |
| Gene ID | 5921 |
| Uniprot ID | RASA1_HUMAN |
Additional Info
| Post Translational Modifications | The N-terminus is blocked. Phosphorylated by SRC and LCK. The phosphorylation SRC inhibits its ability to stimulate the Ras-GTPase activity, whereas phosphorylation by LCK does not display any effect on stimulation activity. |
| Function | Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21.this stimulation may be further increased in the presence of NCK1. |
| Protein Name | Ras Gtpase-Activating Protein 1GapGtpase-Activating ProteinRasgapRas P21 Protein ActivatorP120gap |
| Database Links | Reactome: R-HSA-186763Reactome: R-HSA-3928662Reactome: R-HSA-5218921Reactome: R-HSA-5658442Reactome: R-HSA-8849471 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ras Gtpase-Activating Protein 1 antibodyAnti-Gap antibodyAnti-Gtpase-Activating Protein antibodyAnti-Rasgap antibodyAnti-Ras P21 Protein Activator antibodyAnti-P120gap antibodyAnti-RASA1 antibodyAnti-GAP antibodyAnti-RASA antibody |
Information sourced from Uniprot.org