Anti-Recombinant-RARG antibody [RM1N94] (STJA0023880)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Retinoic Acid Receptor Gamma for use in IF and WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1N94 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | RARG |
| Gene ID | 5916 |
| Uniprot ID | RARG_HUMAN |
Additional Info
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function. |
| Protein Name | Retinoic Acid Receptor GammaRar-GammaNuclear Receptor Subfamily 1 Group B Member 3 |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-5362517Reactome: R-HSA-5617472 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Retinoic Acid Receptor Gamma antibodyAnti-Rar-Gamma antibodyAnti-Nuclear Receptor Subfamily 1 Group B Member 3 antibodyAnti-RARG antibodyAnti-NR1B3 antibody |
Information sourced from Uniprot.org