Anti-Recombinant-PTGES3/P23 antibody [RM2G12] (STJA0025580)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Prostaglandin E Synthase 3 for use in IF, IP and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2G12 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | PTGES3 |
| Gene ID | 10728 |
| Uniprot ID | TEBP_HUMAN |
Additional Info
| Function | Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. |
| Protein Name | Prostaglandin E Synthase 3Cytosolic Prostaglandin E2 SynthaseCpgesHsp90 Co-ChaperoneProgesterone Receptor Complex P23Telomerase-Binding Protein P23 |
| Database Links | Reactome: R-HSA-2162123Reactome: R-HSA-3371497Reactome: R-HSA-3371511Reactome: R-HSA-3371568Reactome: R-HSA-8937144Reactome: R-HSA-8939211Reactome: R-HSA-9018519Reactome: R-HSA-9679191 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Prostaglandin E Synthase 3 antibodyAnti-Cytosolic Prostaglandin E2 Synthase antibodyAnti-Cpges antibodyAnti-Hsp90 Co-Chaperone antibodyAnti-Progesterone Receptor Complex P23 antibodyAnti-Telomerase-Binding Protein P23 antibodyAnti-PTGES3 antibodyAnti-P23 antibodyAnti-TEBP antibody |
Information sourced from Uniprot.org