Anti-Recombinant-POU2F1 antibody [RM1P51] (STJA0023936)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Pou Domain-Class 2-Transcription Factor 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1P51 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | WB: 1:500-1:1000 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | POU2F1 |
| Gene ID | 5451 |
| Uniprot ID | PO2F1_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated by PRKDC. |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. (Microbial infection) In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes. |
| Protein Name | Pou Domain - Class 2 - Transcription Factor 1Nf-A1Octamer-Binding Protein 1Oct-1Octamer-Binding Transcription Factor 1Otf-1 |
| Database Links | Reactome: R-HSA-6785807Reactome: R-HSA-6807505Reactome: R-HSA-749476Reactome: R-HSA-76071Reactome: R-HSA-9018519 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 2 - Transcription Factor 1 antibodyAnti-Nf-A1 antibodyAnti-Octamer-Binding Protein 1 antibodyAnti-Oct-1 antibodyAnti-Octamer-Binding Transcription Factor 1 antibodyAnti-Otf-1 antibodyAnti-POU2F1 antibodyAnti-OCT1 antibodyAnti-OTF1 antibody |
Information sourced from Uniprot.org