Anti-Recombinant-Phospho-EEF2-Thr56/Thr58 antibody [RM1N96] (STJA0023882)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Phospho-Elongation Factor 2-Thr56/Thr58 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1N96 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | WB: 1:500-1:1000 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | EEF2 |
| Gene ID | 1938 |
| Uniprot ID | EF2_HUMAN |
Additional Info
| Function | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. |
| Protein Name | Elongation Factor 2Ef-2 |
| Database Links | Reactome: R-HSA-156902Reactome: R-HSA-5336415Reactome: R-HSA-5358493Reactome: R-HSA-6798695Reactome: R-HSA-8876725 |
| Cellular Localisation | CytoplasmNucleusPhosphorylation By Csk Promotes Cleavage And Sumoylation-Dependent Nuclear Translocation Of The C-Terminal Cleavage Product |
| Alternative Antibody Names | Anti-Elongation Factor 2 antibodyAnti-Ef-2 antibodyAnti-EEF2 antibodyAnti-EF2 antibody |
Information sourced from Uniprot.org