Anti-Recombinant-PCYT1A antibody [RM1X43] (STJA0024720)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Choline-Phosphate Cytidylyltransferase A for use in FC, IF, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1X43 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | FCM: 1:20-1:100 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | PCYT1A |
| Gene ID | 5130 |
| Uniprot ID | PCY1A_HUMAN |
Additional Info
| Post Translational Modifications | The serine residues of the C-terminus are phosphorylated. The inactive soluble form is stabilized by phosphorylation, the active membrane bound form is promoted by anionic lipids or diacylglycerol, and is stabilized by dephosphorylation. Monoubiquitinated by the SCF(FBXL2) complex, leading to proteasomal degradation. |
| Function | Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis. |
| Protein Name | Choline-Phosphate Cytidylyltransferase ACct-AlphaCtp -Phosphocholine Cytidylyltransferase ACct ACt APhosphorylcholine Transferase A |
| Database Links | Reactome: R-HSA-1483191 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinEndoplasmic Reticulum MembraneNucleusIt Can Interconvert Between An Inactive Cytosolic Form And An Active Membrane-Bound Form |
| Alternative Antibody Names | Anti-Choline-Phosphate Cytidylyltransferase A antibodyAnti-Cct-Alpha antibodyAnti-Ctp -Phosphocholine Cytidylyltransferase A antibodyAnti-Cct A antibodyAnti-Ct A antibodyAnti-Phosphorylcholine Transferase A antibodyAnti-PCYT1A antibodyAnti-CTPCT antibodyAnti-PCYT1 antibody |
Information sourced from Uniprot.org