Anti-Recombinant-PCBP1 antibody [RM2G26] (STJA0025594)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Poly (Rc-Binding Protein 1 for use in IP and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2G26 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IP: 1:20-1:50, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | PCBP1 |
| Gene ID | 5093 |
| Uniprot ID | PCBP1_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated.lowers poly(rC)-binding activity. |
| Function | Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing. (Microbial infection) In case of infection by poliovirus, plays a role in initiation of viral RNA replication in concert with the viral protein 3CD. |
| Protein Name | Poly(Rc-Binding Protein 1Alpha-Cp1Heterogeneous Nuclear Ribonucleoprotein E1Hnrnp E1Nucleic Acid-Binding Protein Sub2.3 |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72203 |
| Cellular Localisation | NucleusCytoplasmLoosely Bound In The NucleusMay Shuttle Between The Nucleus And The Cytoplasm |
| Alternative Antibody Names | Anti-Poly(Rc-Binding Protein 1 antibodyAnti-Alpha-Cp1 antibodyAnti-Heterogeneous Nuclear Ribonucleoprotein E1 antibodyAnti-Hnrnp E1 antibodyAnti-Nucleic Acid-Binding Protein Sub2.3 antibodyAnti-PCBP1 antibody |
Information sourced from Uniprot.org