Anti-Recombinant-PBK antibody [RM2L67] (STJA0026031)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Lymphokine-Activated Killer T-Cell-Originated Protein Kinase for use in IHC, IP and WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2L67 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | PBK |
| Gene ID | 55872 |
| Uniprot ID | TOPK_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated.in a cell-cycle dependent manner at mitosis. |
| Function | Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. |
| Protein Name | Lymphokine-Activated Killer T-Cell-Originated Protein KinaseCancer/Testis Antigen 84Ct84Mapkk-Like Protein KinaseNori-3Pdz-Binding KinaseSpermatogenesis-Related Protein KinaseSpkT-Lak Cell-Originated Protein Kinase |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Lymphokine-Activated Killer T-Cell-Originated Protein Kinase antibodyAnti-Cancer/Testis Antigen 84 antibodyAnti-Ct84 antibodyAnti-Mapkk-Like Protein Kinase antibodyAnti-Nori-3 antibodyAnti-Pdz-Binding Kinase antibodyAnti-Spermatogenesis-Related Protein Kinase antibodyAnti-Spk antibodyAnti-T-Lak Cell-Originated Protein Kinase antibodyAnti-PBK antibodyAnti-TOPK antibody |
Information sourced from Uniprot.org