Anti-Recombinant-NSDHL antibody [RM2G56] (STJA0025624)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Sterol-4-Alpha-Carboxylate 3-Dehydrogenase-Decarboxylating for use in IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2G56 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IP: 1:20, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | NSDHL |
| Gene ID | 50814 |
| Uniprot ID | NSDHL_HUMAN |
Additional Info
| Function | Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis. Also plays a role in the regulation of the endocytic trafficking of EGFR. |
| Protein Name | Sterol-4-Alpha-Carboxylate 3-Dehydrogenase - DecarboxylatingProtein H105e3 |
| Database Links | Reactome: R-HSA-191273 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinLipid DropletTrafficking Through The Golgi Is Necessary For Er Membrane Localization |
| Alternative Antibody Names | Anti-Sterol-4-Alpha-Carboxylate 3-Dehydrogenase - Decarboxylating antibodyAnti-Protein H105e3 antibodyAnti-NSDHL antibodyAnti-H105E3 antibody |
Information sourced from Uniprot.org