Anti-Recombinant-NRF1 antibody [RM2H39] (STJA0025706)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Nuclear Respiratory Factor 1 for use in FC, IF, IHC, IP and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2H39 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | FCM: 1:20-1:100, IF: 1:50-1:200, IHC: 1:100-1:200, IP: 1:20-1:50, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | NRF1 |
| Gene ID | 4899 |
| Uniprot ID | NRF1_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylation enhances DNA binding. |
| Function | Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. |
| Protein Name | Nuclear Respiratory Factor 1Nrf-1Alpha Palindromic-Binding ProteinAlpha-Pal |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-2151201Reactome: R-HSA-9841251 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Respiratory Factor 1 antibodyAnti-Nrf-1 antibodyAnti-Alpha Palindromic-Binding Protein antibodyAnti-Alpha-Pal antibodyAnti-NRF1 antibody |
Information sourced from Uniprot.org