Anti-Recombinant-non-muscle Myosin IIB/MYH10 antibody [SM0587] (STJA0010587)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenKLHconjugatedSyntheticpeptidecorrespondingtoMouseMYH10
General Information
| Short Description | Mouse monoclonal anti-Recombinant-non-muscle Myosin IIB/MYH10 for use in WB, IHC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SM0587 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB (H, M, R) 1:500-1:1000IHC/IF (H, M, R) 1:250-1:1000 |
| Formulation | PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
| Storage Instruction | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Target Information
| Gene Symbol | Myh10 |
| Gene ID | 77579 |
| Uniprot ID | MYH10_MOUSE |
| Immunogen | KLHconjugatedSyntheticpeptidecorrespondingtoMouseMYH10 |
Additional Info
| Post Translational Modifications | Phosphorylated by ABL2. |
| Function | Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension.this function is mechanically antagonized by MYH9. Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. |
| Protein Name | Myosin-10Cellular Myosin Heavy Chain - Type BMyosin Heavy Chain 10Myosin Heavy Chain - Non-Muscle IibNon-Muscle Myosin Heavy Chain BNmmhc-BNon-Muscle Myosin Heavy Chain IibNmmhc Ii-BNmmhc-Iib |
| Database Links | Reactome: R-MMU-5627123 |
| Cellular Localisation | Cell ProjectionLamellipodiumColocalizes With Mcc At The Leading Edge Of Migrating Cells |
| Alternative Antibody Names | Anti-Myosin-10 antibodyAnti-Cellular Myosin Heavy Chain - Type B antibodyAnti-Myosin Heavy Chain 10 antibodyAnti-Myosin Heavy Chain - Non-Muscle Iib antibodyAnti-Non-Muscle Myosin Heavy Chain B antibodyAnti-Nmmhc-B antibodyAnti-Non-Muscle Myosin Heavy Chain Iib antibodyAnti-Nmmhc Ii-B antibodyAnti-Nmmhc-Iib antibodyAnti-Myh10 antibody |
Information sourced from Uniprot.org