Anti-Recombinant-MYDGF antibody [RM2M67] (STJA0026130)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJA0026130
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General Information

Short DescriptionRabbit monoclonal anti-Recombinant-Myeloid-Derived Growth Factor for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDRM2M67
IsotypeIgG
ConjugationUnconjugated
PurificationProtein A/G purified from cell culture supernatant
Dilution RangeWB: 1:500-1:1000
Formulation0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide
Storage InstructionSuitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.

Target Information

Gene SymbolMYDGF
Gene ID56005
Uniprot IDMYDGF_HUMAN

Additional Info

Function Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.
Protein Name Myeloid-Derived Growth Factor
Mydgf
Database Links Reactome: R-HSA-381038
Cellular Localisation Secreted
Endoplasmic Reticulum-Golgi Intermediate Compartment
Endoplasmic Reticulum
Golgi Apparatus
The C-Terminal Rtel Motif May Provide Retention In The Endoplasmic Reticulum
Alternative Antibody Names Anti-Myeloid-Derived Growth Factor antibody
Anti-Mydgf antibody
Anti-MYDGF antibody
Anti-C19orf10 antibody

Information sourced from Uniprot.org

Citations

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