Anti-Recombinant-LTB4R antibody [RM2G53] (STJA0025621)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Leukotriene B4 Receptor 1 for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2G53 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:100-1:200, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | LTB4R |
| Gene ID | 1241 |
| Uniprot ID | LT4R1_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated by GRK6 upon leukotriene B4 binding.which promotes desensitization. |
| Function | Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. |
| Protein Name | Leukotriene B4 Receptor 1Ltb4-R 1Ltb4-R1Chemoattractant Receptor-Like 1G-Protein Coupled Receptor 16P2y Purinoceptor 7P2y7 |
| Database Links | Reactome: R-HSA-391906Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Leukotriene B4 Receptor 1 antibodyAnti-Ltb4-R 1 antibodyAnti-Ltb4-R1 antibodyAnti-Chemoattractant Receptor-Like 1 antibodyAnti-G-Protein Coupled Receptor 16 antibodyAnti-P2y Purinoceptor 7 antibodyAnti-P2y7 antibodyAnti-LTB4R antibodyAnti-BLT antibodyAnti-BLT1 antibodyAnti-BLTR antibodyAnti-CMKRL1 antibodyAnti-GPR16 antibodyAnti-P2RY7 antibody |
Information sourced from Uniprot.org