Anti-Recombinant-LLGL1 antibody [RM2G24] (STJA0025592)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Lethal (2 Giant Larvae Protein Homolog 1 for use in IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2G24 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IP: 1:20, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | LLGL1 |
| Gene ID | 3996 |
| Uniprot ID | L2GL1_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated at least at Ser-663 by PRKCI. |
| Function | Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane. |
| Protein Name | Lethal(2 Giant Larvae Protein Homolog 1LlglDlg4Hugl-1Human Homolog To The D-Lgl Gene Protein |
| Database Links | |
| Cellular Localisation | Early Endosome MembraneGolgi ApparatusTrans-Golgi Network MembraneGolgi Apparatus MembraneCell ProjectionAxonCytoplasmCytoskeletonLocalized To The Lateral Membrane During The Polarization And Formation Cell-Cell ContactsEnriched In Developing Axons |
| Alternative Antibody Names | Anti-Lethal(2 Giant Larvae Protein Homolog 1 antibodyAnti-Llgl antibodyAnti-Dlg4 antibodyAnti-Hugl-1 antibodyAnti-Human Homolog To The D-Lgl Gene Protein antibodyAnti-LLGL1 antibodyAnti-DLG4 antibodyAnti-HUGL antibodyAnti-HUGL1 antibody |
Information sourced from Uniprot.org