Anti-Recombinant-KLKB1 antibody [RM1J31] (STJA0023421)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Plasma Kallikrein for use in IHC, IP and WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1J31 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:100-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | KLKB1 |
| Gene ID | 3818 |
| Uniprot ID | KLKB1_HUMAN |
Additional Info
| Function | Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. |
| Protein Name | Plasma KallikreinFletcher FactorKininogeninPlasma PrekallikreinPkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-1592389Reactome: R-HSA-9657688Reactome: R-HSA-9657689 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Plasma Kallikrein antibodyAnti-Fletcher Factor antibodyAnti-Kininogenin antibodyAnti-Plasma Prekallikrein antibodyAnti-Pkk Cleaved Into - Plasma Kallikrein Heavy Chain - Plasma Kallikrein Light Chain antibodyAnti-KLKB1 antibodyAnti-KLK3 antibody |
Information sourced from Uniprot.org