Anti-Recombinant-KIF23 antibody [RM2C16] (STJA0025188)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Kinesin-Like Protein Kif23 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2C16 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | KIF23 |
| Gene ID | 9493 |
| Uniprot ID | KIF23_HUMAN |
Additional Info
| Post Translational Modifications | Ubiquitinated. Deubiquitinated by USP8/UBPY. |
| Function | Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. |
| Protein Name | Kinesin-Like Protein Kif23Kinesin-Like Protein 5Mitotic Kinesin-Like Protein 1 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-6811434Reactome: R-HSA-68884Reactome: R-HSA-983189 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonSpindleMidbodyMidbody RingLocalizes To The Interzone Of Mitotic SpindlesDetected At The Midbody During Later Stages Of Mitotic Cytokinesis |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif23 antibodyAnti-Kinesin-Like Protein 5 antibodyAnti-Mitotic Kinesin-Like Protein 1 antibodyAnti-KIF23 antibodyAnti-KNSL5 antibodyAnti-MKLP1 antibody |
Information sourced from Uniprot.org