Anti-Recombinant-KCTD21 antibody [RM2H72] (STJA0025739)

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STJA0025739
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-Btb/Poz Domain-Containing Protein Kctd21 is suitable for use in Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM2H72
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: WB: 1:500-1:1000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: KCTD21
Gene ID: 283219
Uniprot ID: KCD21_HUMAN
Function Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1.the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB).
Protein Name Btb/Poz Domain-Containing Protein Kctd21
Kcash2 Protein
Potassium Channel Tetramerization Domain-Containing Protein 21
Alternative Antibody Names Anti-Btb/Poz Domain-Containing Protein Kctd21 antibody
Anti-Kcash2 Protein antibody
Anti-Potassium Channel Tetramerization Domain-Containing Protein 21 antibody
Anti-KCTD21 antibody

Information sourced from Uniprot.org

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