Anti-Recombinant-IVL/Involucrin antibody [RM1L10] (STJA0023598)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Involucrin for use in FC, IHC and WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1L10 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | FCM: 1:20-1:100 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | IVL |
| Gene ID | 3713 |
| Uniprot ID | INVO_HUMAN |
Additional Info
| Post Translational Modifications | Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide. |
| Function | Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. |
| Protein Name | Involucrin |
| Database Links | Reactome: R-HSA-6809371Reactome: R-HSA-9725554 |
| Cellular Localisation | CytoplasmConstituent Of The Scaffolding Of The Cornified Envelope |
| Alternative Antibody Names | Anti-Involucrin antibodyAnti-IVL antibody |
Information sourced from Uniprot.org