Anti-Recombinant-IL1RN/IL-1ra/IL1F3 antibody [RM1Q88] (STJA0024072)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Interleukin-1 Receptor Antagonist Protein for use in IF, IHC, IP and WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1Q88 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | IL1RN |
| Gene ID | 3557 |
| Uniprot ID | IL1RA_HUMAN |
Additional Info
| Function | Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens. |
| Protein Name | Interleukin-1 Receptor Antagonist ProteinIl-1rnIl-1raIrapIcil-1raIl1 InhibitorAnakinra |
| Database Links | Reactome: R-HSA-6783783Reactome: R-HSA-9020702 |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmIsoform 3: CytoplasmIsoform 4: Cytoplasm |
| Alternative Antibody Names | Anti-Interleukin-1 Receptor Antagonist Protein antibodyAnti-Il-1rn antibodyAnti-Il-1ra antibodyAnti-Irap antibodyAnti-Icil-1ra antibodyAnti-Il1 Inhibitor antibodyAnti-Anakinra antibodyAnti-IL1RN antibodyAnti-IL1F3 antibodyAnti-IL1RA antibody |
Information sourced from Uniprot.org