Anti-Recombinant-HOPX antibody [RM2T07] (STJA0026664)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-HOPX for use in IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2T07 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IP: 1:20, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | Hopx |
| Gene ID | 74318 |
| Uniprot ID | HOP_MOUSE |
Additional Info
| Function | Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding. |
| Protein Name | Homeodomain-Only ProteinHomeobox-Only ProteinOdd Homeobox Protein 1Mob1 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmIt Is Cytoplasmic |
| Alternative Antibody Names | Anti-Homeodomain-Only Protein antibodyAnti-Homeobox-Only Protein antibodyAnti-Odd Homeobox Protein 1 antibodyAnti-Mob1 antibodyAnti-Hopx antibodyAnti-Hod antibodyAnti-Hop antibodyAnti-Ob1 antibody |
Information sourced from Uniprot.org