Anti-Recombinant-HLTF antibody [RM2F50] (STJA0025519)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Helicase-Like Transcription Factor for use in IF and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2F50 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | HLTF |
| Gene ID | 6596 |
| Uniprot ID | HLTF_HUMAN |
Additional Info
| Function | Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity.This activity may be required for transcriptional activation or repression of specific target promoters. These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA. |
| Protein Name | Helicase-Like Transcription FactorDna-Binding Protein/Plasminogen Activator Inhibitor 1 RegulatorHip116Ring Finger Protein 80Ring-Type E3 Ubiquitin Transferase HltfSwi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 3Sucrose Nonfermenting Protein 2-Like 3 |
| Database Links | Reactome: R-HSA-8866654 |
| Cellular Localisation | CytoplasmNucleusNucleolusNucleoplasmNuclear Localization Is Stimulated By Progesterone |
| Alternative Antibody Names | Anti-Helicase-Like Transcription Factor antibodyAnti-Dna-Binding Protein/Plasminogen Activator Inhibitor 1 Regulator antibodyAnti-Hip116 antibodyAnti-Ring Finger Protein 80 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Hltf antibodyAnti-Swi/Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 3 antibodyAnti-Sucrose Nonfermenting Protein 2-Like 3 antibodyAnti-HLTF antibodyAnti-HIP116A antibodyAnti-RNF80 antibodyAnti-SMARCA3 antibodyAnti-SNF2L3 antibodyAnti-ZBU1 antibody |
Information sourced from Uniprot.org