Anti-Recombinant-HJURP antibody [RM2S94] (STJA0026652)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Holliday Junction Recognition Protein for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2S94 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:50-1:100, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | HJURP |
| Gene ID | 55355 |
| Uniprot ID | HJURP_HUMAN |
Additional Info
| Function | Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions. |
| Protein Name | Holliday Junction Recognition Protein14-3-3-Associated Akt SubstrateFetal Liver-Expressing Gene 1 ProteinUp-Regulated In Lung Cancer 9 |
| Database Links | Reactome: R-HSA-606279 |
| Cellular Localisation | NucleusNucleolusChromosomeCentromereLocalizes In Centromeres During Late Telophase And Early G1When Cenpa Nucleosomes Are AssembledLocalizes To Nucleolus During S PhaseNucleolus Site Being Often Related To Storage |
| Alternative Antibody Names | Anti-Holliday Junction Recognition Protein antibodyAnti-14-3-3-Associated Akt Substrate antibodyAnti-Fetal Liver-Expressing Gene 1 Protein antibodyAnti-Up-Regulated In Lung Cancer 9 antibodyAnti-HJURP antibodyAnti-FAKTS antibodyAnti-FLEG1 antibodyAnti-URLC9 antibody |
Information sourced from Uniprot.org