Anti-Recombinant-HHEX antibody [RM2C30] (STJA0025202)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Hematopoietically-Expressed Homeobox Protein Hhex for use in IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2C30 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IP: 1:20-1:50, WB: 1:1000-1:2000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | HHEX |
| Gene ID | 3087 |
| Uniprot ID | HHEX_HUMAN |
Additional Info
| Function | Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Activator of WNT-mediated transcription in conjunction with CTNNB1. Establishes anterior identity at two levels.acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. Inhibits EIF4E-mediated mRNA nuclear export. May play a role in hematopoietic differentiation. |
| Protein Name | Hematopoietically-Expressed Homeobox Protein HhexHomeobox Protein HexHomeobox Protein PrhProline-Rich Homeodomain Protein |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | NucleusNuclear BodyCytoplasm |
| Alternative Antibody Names | Anti-Hematopoietically-Expressed Homeobox Protein Hhex antibodyAnti-Homeobox Protein Hex antibodyAnti-Homeobox Protein Prh antibodyAnti-Proline-Rich Homeodomain Protein antibodyAnti-HHEX antibodyAnti-HEX antibodyAnti-PRH antibodyAnti-PRHX antibody |
Information sourced from Uniprot.org