| Function | Isoform 1: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Isoform 2: Has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers. |
| Protein Name | Beta-GalactosidaseAcid Beta-GalactosidaseLactaseElastin Receptor 1 |
| Database Links | Reactome: R-HSA-2022857Reactome: R-HSA-2024096Reactome: R-HSA-2206308Reactome: R-HSA-4085001Reactome: R-HSA-4341670Reactome: R-HSA-6798695Reactome: R-HSA-9840310 |
| Cellular Localisation | Isoform 1: LysosomeIsoform 2: CytoplasmPerinuclear RegionLocalized To The Perinuclear Area Of The Cytoplasm But Not To Lysosomes |
| Alternative Antibody Names | Anti-Beta-Galactosidase antibodyAnti-Acid Beta-Galactosidase antibodyAnti-Lactase antibodyAnti-Elastin Receptor 1 antibodyAnti-GLB1 antibodyAnti-ELNR1 antibody |
Information sourced from Uniprot.org
