Anti-Recombinant-GFAP antibody (411-422 aa) [N206A/8] {FL650 Ex: 655 nm, Em: 676 nm} (STJA0040458)
SPECIFICATIONS
ClonalityMonoclonal
HostChicken
ConjugationFL650 Ex: 655 nm, Em: 676 nm
IsotypeIgY
ImmunogenSynthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP (accession number P14136)
General Information
| Short Description | Chicken monoclonal anti-Recombinant-GFAP (411-422 aa) for use in ICC and IHC in Drosophila, Guinea Pig, Human, Mouse, Polar Bear and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ICC/IHC |
| Host | Chicken |
| Reactivity | Drosophila/Guinea Pig/Human/Mouse/Polar Bear/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | N206A/8 |
| Isotype | IgY |
| Conjugation | FL650 Ex: 655 nm, Em: 676 nm |
| Concentration | 0.5 mg/mL |
| Purification | Purified by affinity chromatography |
| Formulation | 1X PBS, 0.05% Sodium Azide pH 7.4 |
| Storage Instruction | Aliquot and store at ≤-20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap. |
Target Information
| Gene Symbol | GFAP |
| Gene ID | 2670 |
| Uniprot ID | GFAP_HUMAN |
| Immunogen | Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP (accession number P14136) |
| Immunogen Region | 411-422 aa |
| Immunogen Sequence | Human |
| Specificity | Cross-reacts with GFAP-R416W and other GFAP mutant proteins. Does not cross-react with other proteins (based on KO validation results). |
Additional Info
| Tissue Specificity | Expressed in cells lacking fibronectin. |
| Post Translational Modifications | Phosphorylated by PKN1. |
| Function | GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. |
| Protein Name | Glial Fibrillary Acidic ProteinGfap |
| Database Links | Reactome: R-HSA-1251985Reactome: R-HSA-9613829 |
| Cellular Localisation | CytoplasmAssociated With Intermediate Filaments |
| Alternative Antibody Names | Anti-Glial Fibrillary Acidic Protein antibodyAnti-Gfap antibodyAnti-GFAP antibody |
Information sourced from Uniprot.org