![Anti-Recombinant-GAP43 antibody [SR0564] (STJA0010564)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180459/404254/STJA0010564_2__02225.1738951315.jpg?c=1 "Anti-Recombinant-GAP43 antibody [SR0564] (STJA0010564)")
![Anti-Recombinant-GAP43 antibody [SR0564] (STJA0010564)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/180459/404254/STJA0010564_2__02225.1738951315.jpg?c=1 "Anti-Recombinant-GAP43 antibody [SR0564] (STJA0010564)")
Anti-Recombinant-GAP43 antibody [SR0564] (STJA0010564)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenKLH conjugated Synthetic peptide corresponding to Mouse GAP43
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-GAP43 for use in WB, IHC and IF in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SR0564 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB (M, R) 1:500-1:1000IHC/IF (M, R) 1:500-1:1000 |
| Formulation | PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol. |
| Storage Instruction | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Target Information
| Gene Symbol | Gap43 |
| Gene ID | 14432 |
| Uniprot ID | NEUM_MOUSE |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse GAP43 |
Additional Info
| Post Translational Modifications | Phosphorylated. Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity. Palmitoylated by ZDHHC3. Palmitoylation is regulated by ARF6 and is essential for plasma membrane association and axonal and dendritic filopodia induction. Deacylated by LYPLA2. |
| Function | This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction. |
| Protein Name | NeuromodulinAxonal Membrane Protein Gap-43Calmodulin-Binding Protein P-57Growth-Associated Protein 43 |
| Database Links | Reactome: R-MMU-373760 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCell ProjectionGrowth Cone MembraneSynapseFilopodium MembranePerikaryonDendriteAxonCytoplasmCytoplasmic Surface Of Growth Cone And Synaptic Plasma Membranes |
| Alternative Antibody Names | Anti-Neuromodulin antibodyAnti-Axonal Membrane Protein Gap-43 antibodyAnti-Calmodulin-Binding Protein P-57 antibodyAnti-Growth-Associated Protein 43 antibodyAnti-Gap43 antibodyAnti-Basp2 antibody |
Information sourced from Uniprot.org