Anti-Recombinant-FYB1 antibody [RM1D51] (STJA0022946)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Fyn-Binding Protein 1 for use in IF, IHC and WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1D51 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | FYB1 |
| Gene ID | 2533 |
| Uniprot ID | FYB1_HUMAN |
Additional Info
| Post Translational Modifications | T-cell receptor ligation leads to increased tyrosine phosphorylation. |
| Function | Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Modulates the expression of IL2. Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells. |
| Protein Name | Fyn-Binding Protein 1Adhesion And Degranulation Promoting Adaptor ProteinAdapFyb-120/130P120/P130Fyn-T-Binding ProteinSlap-130Slp-76-Associated Phosphoprotein |
| Database Links | Reactome: R-HSA-202433Reactome: R-HSA-391160 |
| Cellular Localisation | CytoplasmNucleusCell JunctionColocalizes With Tmem47 At Cell-Cell Contacts In Podocytes |
| Alternative Antibody Names | Anti-Fyn-Binding Protein 1 antibodyAnti-Adhesion And Degranulation Promoting Adaptor Protein antibodyAnti-Adap antibodyAnti-Fyb-120/130 antibodyAnti-P120/P130 antibodyAnti-Fyn-T-Binding Protein antibodyAnti-Slap-130 antibodyAnti-Slp-76-Associated Phosphoprotein antibodyAnti-FYB1 antibodyAnti-FYB antibodyAnti-SLAP130 antibody |
Information sourced from Uniprot.org