Anti-Recombinant-FRAT1 antibody [RM2RM73] (STJA0026532)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Proto-Oncogene Frat1 for use in IF, IP and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IP/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM2RM73 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200, IP: 1:20, WB: 1:500-1:1000 |
| Formulation | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium Azide |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | FRAT1 |
| Gene ID | 10023 |
| Uniprot ID | FRAT1_HUMAN |
Additional Info
| Function | Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. |
| Protein Name | Proto-Oncogene Frat1Frequently Rearranged In Advanced T-Cell Lymphomas 1Frat-1 |
| Database Links | Reactome: R-HSA-196299Reactome: R-HSA-4641262 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Proto-Oncogene Frat1 antibodyAnti-Frequently Rearranged In Advanced T-Cell Lymphomas 1 antibodyAnti-Frat-1 antibodyAnti-FRAT1 antibody |
Information sourced from Uniprot.org