Anti-Recombinant-FMO3 antibody [RM1U24] (STJA0024404)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Flavin-Containing Monooxygenase 3 for use in IF, IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1U24 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IF: 1:50-1:200 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | FMO3 |
| Gene ID | 2328 |
| Uniprot ID | FMO3_HUMAN |
Additional Info
| Function | Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation. |
| Protein Name | Flavin-Containing Monooxygenase 3 Dimethylaniline Monooxygenase N-Oxide-Forming 3Dimethylaniline Oxidase 3Fmo IiFmo Form 2Hepatic Flavin-Containing Monooxygenase 3Fmo 3Trimethylamine Monooxygenase |
| Database Links | Reactome: R-HSA-217271Reactome: R-HSA-5579019 |
| Cellular Localisation | Microsome MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Flavin-Containing Monooxygenase 3 antibodyAnti-Dimethylaniline Monooxygenase N-Oxide-Forming 3 antibodyAnti-Dimethylaniline Oxidase 3 antibodyAnti-Fmo Ii antibodyAnti-Fmo Form 2 antibodyAnti-Hepatic Flavin-Containing Monooxygenase 3 antibodyAnti-Fmo 3 antibodyAnti-Trimethylamine Monooxygenase antibodyAnti-FMO3 antibody |
Information sourced from Uniprot.org