Anti-Recombinant-FDX1 antibody [RM1M57] (STJA0023744)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal anti-Recombinant-Adrenodoxin-Mitochondrial for use in IHC, IP and WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | RM1M57 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A/G purified from cell culture supernatant |
| Dilution Range | IHC: 1:50-1:100 |
| Formulation | 0.01M PBS |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | FDX1 |
| Gene ID | 2230 |
| Uniprot ID | ADX_HUMAN |
Additional Info
| Function | Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. |
| Protein Name | Adrenodoxin - MitochondrialAdrenal FerredoxinFerredoxin-1Hepatoredoxin |
| Database Links | Reactome: R-HSA-1362409Reactome: R-HSA-196108Reactome: R-HSA-211976Reactome: R-HSA-2395516Reactome: R-HSA-5579026Reactome: R-HSA-9857492 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Adrenodoxin - Mitochondrial antibodyAnti-Adrenal Ferredoxin antibodyAnti-Ferredoxin-1 antibodyAnti-Hepatoredoxin antibodyAnti-FDX1 antibodyAnti-ADX antibody |
Information sourced from Uniprot.org