Anti-Recombinant-FAM20A antibody (500-600) [S4947RM] (STJ11104947)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Recombinant-Pseudokinase Fam20a (500-600) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4947RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:2000-1:20000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FAM20A |
| Gene ID | 54757 |
| Uniprot ID | FA20A_HUMAN |
| Immunogen Region | 500-600 |
| Immunogen Sequence | AIFDFLIGNMDRHHYEMFTK FGDDGFLIHLDNARGFGRHS HDEISILSPLSQCCMIKKKT LLHLQLLAQADYRLSDVMRE SLLEDQLSPVLTEPHLLALD R |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human FAM20A (NP_060035.2). |
Additional Info
| Tissue Specificity | Highly expressed in lung and liver. Intermediate levels in thymus and ovary. |
| Post Translational Modifications | N-glycosylated. |
| Function | Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals. |
| Protein Name | Pseudokinase Fam20a |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedGolgi ApparatusEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Pseudokinase Fam20a antibodyAnti-FAM20A antibodyAnti-UNQ9388 antibodyAnti-PRO34279 antibody |
Information sourced from Uniprot.org