Anti-Recombinant-FAM20A antibody (500-600) [S4947RM] (STJ11104947)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11104947
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General Information

Short DescriptionRabbit monoclonal Recombinant-Pseudokinase Fam20a (500-600) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDS4947RM
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:2000-1:20000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolFAM20A
Gene ID54757
Uniprot IDFA20A_HUMAN
Immunogen Region500-600
Immunogen SequenceAIFDFLIGNMDRHHYEMFTK FGDDGFLIHLDNARGFGRHS HDEISILSPLSQCCMIKKKT LLHLQLLAQADYRLSDVMRE SLLEDQLSPVLTEPHLLALD R
SpecificityA synthetic peptide corresponding to a sequence within amino acids 500-600 of human FAM20A (NP_060035.2).

Additional Info

Tissue Specificity Highly expressed in lung and liver. Intermediate levels in thymus and ovary.
Post Translational Modifications N-glycosylated.
Function Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals.
Protein Name Pseudokinase Fam20a
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Golgi Apparatus
Endoplasmic Reticulum
Alternative Antibody Names Anti-Pseudokinase Fam20a antibody
Anti-FAM20A antibody
Anti-UNQ9388 antibody
Anti-PRO34279 antibody

Information sourced from Uniprot.org

Citations

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